Heartache.

WASHINGTON – Sales of Hillary Rodham Clinton’s new memoir, “Hard Choices,” declined 43.5 percent to 48,000 copies in its second week on the shelves, according to Nielsen BookScan.

The sales figures put pressure on the publisher, Simon & Schuster, which paid Mrs. Clinton a multimillion-dollar advance to write about her time at the State Department and has invested heavily in the book’s rollout, one of the biggest of the year.

About 85,000 copies were sold in the week after the book’s June 10 release, according to BookScan, a subscription service that tracks sales at over 80 percent of book vendors in the United States. Those figures do not include e-books, which increased sales by about 15 percent, to roughly 100,000 electronic and hardcover copies.

First-week sales typically account for about 30 percent of the total, thanks to the publicity blitzes that accompany publishers’ biggest releases. That means “Hard Choices” could fall far short of the one million copies that Simon & Schuster shipped to bookstores, industry executives said. (Publishers sell books on consignment and must take back copies that do not sell in the stores.)

The second-week figures also increase the likelihood that Simon & Schuster will not sell enough books to make up for Mrs. Clinton’s advance, said a publishing executive who did not want to speak on the record about a competitor’s book.